EAST RUTHERFORD, N.J. — Chip Kelly’s up-tempo offense didn’t keep the New York Giants winless.
It was the Philadelphia Eagles’ backup quarterback and a bottom-ranked defense that sent Tom Coughlin and the Giants to a 36-21 defeat Sunday and their worst start since the 1987 strike season when the NFL used replacement players for three games.
Replacing an injured Michael Vick late in the second quarter, Nick Foles led four scoring drives and threw two fourth-quarter touchdown passes as Philadelphia (2-3) got back on track after three straight losses.
“Mike was hurt, it was my job to go in there and get a win,” said Foles, who completed 16 of 25 for 197 yards, including TD tosses of 25 yards to Brent Celek and 5 yards to DeSean Jackson.
The Eagles defense was just as good. It intercepted Eli Manning three times with the game on the line in the fourth quarter and forced four turnovers, leading to 17 points.
The Giants’ 0-5 start is their worst in a non-strike year since 1979 when Ray Perkins took over as coach.
Vick, who ran for a team-high 79 yards and threw for another 105, left the game with a hamstring injury late in the second quarter after a 13-yard scramble.
David Wilson scored on a 5-yard run for the Giants and Manning threw two touchdowns to Rueben Randle, a former LSU standout, in the third quarter to give New York a 21-19 lead.
49ers 34, Texans 3: In San Francisco, Tramaine Brock intercepted Matt Schaub’s first pass of the night and returned it 18 yards for a touchdown, Schaub threw three interceptions in all before the embattled quarterback got replaced in the fourth, and San Francisco pounded Houston.
Colin Kaepernick threw a 64-yard touchdown pass to Vernon Davis and Frank Gore ran for 81 yards and a score in his second straight impressive prime-time game.
The 49ers (3-2) are right back in the NFC West race with Seattle after the Seahawks (4-1) lost at Indianapolis.
Anthony Dixon added a 2-yard touchdown run for the NFC champions.
Chiefs 26, Titans 17: In Nashville, Jamaal Charles scored a 1-yard touchdown with 6:23 left, and Kansas City kept up its perfect start after rallying to beat Tennessee.
The Chiefs (5-0) are off to their best start since 2003, when they won their first nine games. This win came despite blowing a 13-0 halftime lead in this early AFC showdown between these surprising teams bouncing back after losing seasons.
The Titans (3-2) couldn’t have been more out of synch in the first half with Ryan Fitzpatrick starting for Jake Locker sidelined with his sprained right hip. He missed his first five passes and went three-and-out on his first five series before guiding Tennessee to 17 straight points in the second half.
Charles put the Chiefs ahead to stay, and they intercepted Fitzpatrick twice in the final 6:14. Ryan Succop kicked four field goals, including a 48-yarder.
RAVENS 26, DOLPHINS 23: In Miami Garden, Fla., Justin Tucker kicked a 44-yard field goal to put the Baltimore Ravens ahead with 1:42 left, and they withstood a frantic comeback bid.
Ryan Tannehill completed a 46-yard pass to Brandon Gibson on fourth down to keep Miami’s hopes alive, but Caleb Sturgis then missed a 57-yard field goal attempt wide left with 33 seconds to go.
The Ravens (3-2) bounced back from a loss last week at Buffalo and won on the road for the first time this season. The Dolphins (3-2) lost their second game in a row.
Baltimore moved 34 yards to set up Tucker’s game-winning field goal, his fourth of the day. The Ravens ran for a season-high 133 yards, and Joe Flacco threw for 269 yards.
PACKERS 22, LIONS 9: In Green Bay, Wis., James Jones caught a long touchdown pass from Aaron Rodgers, and the Packers defense contained the undermanned Lions.
Mason Crosby kicked five field goals. The Packers’ offense struggled to get into the end zone until Rodgers found Jones on an 83-yard completion down the left sideline for a 16-3 lead late in the third quarter.
It provided enough of a cushion for a defense that had the luxury of facing the Lions minus star receiver Calvin Johnson, out with a knee injury. Penalties also bogged down Detroit.
The Packers extended their winning streak in Wisconsin over the Lions to 23.
Cardinals 22, Panthers 6: In Glendale, Ariz., Arizona sacked Cam Newton seven times, once for a safety, and intercepted him on three occasions to overcome a sluggish offensive performance, and the Cardinals beat Carolina.
Daryl Washington, back after serving a four-game suspension for violating the NFL’s substance abuse policy, had two sacks and an interception for Arizona (3-2).
Calais Campbell had two sacks, one for Arizona’s first regular-season safety in nine years, the other forcing a game-clinching fumble. Karlos Dansby also had two sacks and an interception.
Carolina (1-3), playing for the first time since a 38-0 victory over the New York Giants two weeks ago, managed only Graham Gano’s field goals of 22 and 51 yards.
Arizona’s Carson Palmer threw for a touchdown but was intercepted three times.
RAMS 34, JAGUARS 20: In St. Louis, Sam Bradford threw three touchdown passes and Matt Giordano’s 82-yard interception return was one of several big plays from the St. Louis defense against winless Jacksonville.
Austin Pettis’ 31-yard TD catch with 5:45 to go was his second of the day and put the Rams (2-3) up by two scores. St. Louis, which had trailed by double digits in every game, established control with a 17-point second quarter after Jacksonville (0-5) had a pair of early leads.
Jaguars quarterback Blaine Gabbert injured his left hamstring in the third quarter.
Rookie left tackle Luke Joeckel was carted off with a right ankle injury in the first.
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